Erectile dysfunction, hi-tech therapeutic novelties: shockwaves, chewing gum and gel. Cures of the future for erectile dysfunction?
Shock waves, chewing gums and gels
These are new hi-tech treatments that have the characteristic of being less falsifiable but equally effective, to protect the health of patients. It ranges from shockwaves on the penis, effective for 70% of cases of mild or moderate erectile dysfunction and able to return a rewarding sex life without more need for oral biofilm drugs, chewing-gum with a rapid effect for a increasingly natural sexuality, and finally, the gel for local use, useful for patients who do not tolerate the side effects of the pills. We are finally in a post-pills era of love, where technology guarantees state-of-the-art therapies, above all not clonable, safer, quick and effective, at the same costs.
The 'blue pill' has been an excellent drug and has opened the way but it is also the most counterfeited market: about a third of men who buy drugs to solve erectile dysfunction resort to self-administration and often get them on the web, where sildenafil also costs ten times less than the pharmacy but does not guarantee the presence of adequate quantities of product or a good quality: the unauthorized pills, which mainly come from India and China, often contain abnormal dosages, up to double the amount due; or they have no active ingredient. Above all, in 8.5% of the cases there were toxic or poisonous substances, even those capable of causing permanent damage.
With shockwave therapy, doctors can finally prevent erectile dysfunction (ED), at its first signs, returning to a satisfying and spontaneous sexuality. The disease can finally be treated, abandon drugs and return to satisfying and spontaneous sexuality. This is the biggest revolution in the treatment of erectile dysfunction since the introduction of Viagra. Males who suffer from a more severe form of erectile dysfunction and do not respond to drugs (oral or intracavernous injection) finally have the possibility of responding to the simplest therapies.
All this is possible thanks to a revolutionary therapy that uses low intensity linear shockwave applied to the cavernous bodies of the penis. The results of the experiments, started more than 15 years ago on animals, have provided evidence that the low intensity shock waves (LISWT) stimulate the creation of new blood vessel networks in the treated tissue. The process, called neoangiogenesis, leads to the formation of a new vascular system in the organs exposed to shock waves.
Shockwave therapy has been studied and used in many fields of medicine for decades. High-intensity shockwaves are used for crushing calculations. Medium-strength waves, thanks to their anti-inflammatory properties, are used to treat a wide range of orthopedic conditions such as broken fractures, tendonitis and bursitis. Low intensity shock waves, which have the property to regenerate the vascular system, are used in the treatment of chronic wounds, peripheral neuropathies and to induce the regeneration of small coronary vessels of the heart in patients suffering from angina and can not undergo coronary surgery or angioplasty.
The therapy improves the vascularization of the heart and is also effective for the penis. In fact, 80% of cases of erectile dysfunction have a vascular cause. If the Linear Waves of Low Intensity are applied to the cavernous bodies of the penis they regenerate the vascular tissue increasing the blood supply to the erectile tissue and allowing the achievement and maintenance of a full erection. This is the case of chewing gums, oral biofilms that are put on the tongue and melt within a few seconds:here too, technology is the key word. The active ingredients are in fact introduced into these vectors that melt when in contact with saliva with a very advanced process. This allows faster absorption in the mouth, avoiding the passage in the stomach and in the liver that can destroy a large amount of medication. All this makes the biofilm faster and more active, for an increasingly satisfying and natural sexual activity of the couple.
And the technology is also advanced in the intraurethral gel based on alprostadil, just arrived at the pharmacy, which is applied locally at the time of the relationship: it is a prostaglandin linked to an inert substance that transports it from the urethral canal into the penis, where it is needed. It has a very rapid vasodilatory effect that promotes erection and is now used by those who cannot stand the side effects of other systemic drugs and patients who prefer a substance that acts and is introduced exactly where it is needed.
Alprostadil
Alprostadil (trade name Caverject) is a vasodilator drug used in the treatment of erectile dysfunction (difficulty in achieving and / or maintaining a satisfactory erection). For this purpose, it is injected directly into the corpus cavernosum of the penis, determining erections that are valid as needed even in patients with a severely compromised cycle or with alterations of the nervous system.
In myelolysis, the rate of positive response (in terms of satisfactory erection) to the use of alprostadil appears to be higher than that induced by oral sildenafil (Viagra); however, the lower the practicality of use and the greater the risks of local complications and undesirable effects on the psychological level. Unlike Viagra, alprostadil supports the physiological erection mechanism even in the absence of sexual stimulation. The action begins approximately 5-20 minutes after injection and is maintained for about an hour, often even after ejaculation. The use of alprostadil in intraurethral suppositories (small tablets, the size of half grain of rice, to be inserted into the urethra with a special applicator), rather than by direct injection to the base of the penis, produces a much lower action than the injectable formulation, resulting effective in producing a satisfactory erection in only 30-40% of patients with erectile dysfunction (instead of 80% and above).
Alprostadil is able to induce erection by direct release of smooth muscle; shares, in this sense, the same action of phentolamine and papaverine, alkaloid extracted from opium but without any narcotic effects. Often the two substances are combined together in pharmaceutical specialties. Aprostadil is a synthetic analogue of prostaglandin 1 (PGE1), a substance with marked vasodilatory properties. The drug is injected at the base of the penis a few minutes before sexual intercourse. The maximum recommended frequency of administration should not be greater than one injection per day and three per week, with at least 24 hours of interval between doses.
Locally, the injection of alprostadil (Caverject) can produce mild or moderate pain in the penis, prolonged erections (lasting 4-6 hours), bleeding and priapism. The usual injection range is 5-20 μg of alprostadil, up to a maximum of 60 μg. It starts normally with a dose of a few μg and evaluates the result in terms of stiffness and penetrative capacity with the doctor; of course, before taking the injections of alprostadil independently, a training and a preventive andrological visit is necessary. Along with chewing-gum is an innovative solution that allows you to regain sexual serenity in complete safety, without the risk of side effects from counterfeited products because they are both technologies very difficult to falsify.
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