Peyronie’s Disease as an Overlooked Cause of ED
Even before adulthood many men start noticing that their penises are of unusual form. Sometimes slight deflections are quite normal and common for most males, but in sometimes they may be the signals of the so-called Peyronie's disease that is mostly characterized by an abnormally curved penis. What is this disorder and what health dangers can it provoke? Many men with curved penises ask these questions during a private consultation with the expert team of Canadian Pharmacy. We decided to join all answers in one post. Here is what we researched about Peyronie’s disease and its impact on erectile dysfunction.
What is Peyronie's disease?
This disease has another medical term and is always characterized as an inflammatory, benign condition that affects the tunica albuginea of corpus cavernosum of a penis.
Multiple seals or plaques start to develop. These formations can easily fill the back of a penis. Sometimes they develop on the opposite sides of urethra. Sometimes patients have overgrowth of scar tissue (fibrosis) of the corpus cavernosum. Medical statistics showed that about 30% of patients with this diagnosis recorded fibrosis.
Unfortunately, these changes lead to erectile dysfunction and also unbearable pain starts to develop during sexual intercourse, making it virtually impossible. Frequently patients are turning to urologists such complaints and the diagnosis usually results as Peyronie’s disease. However, you can be encouraged by the fact that this rare disease affects only 1% of the world’s male population.
Causes of the disease
For this unlucky 1% of men the following info will be very useful. According to the research made by Canadian Pharmacy, Peyronie's disease was at first found and described by a French physician with the eponymous name in 1743, but experts cannot even now confidently tell you how this disease develops in a body and what factors exactly make it.
Among the modern medical experts, including the team of Canadian Pharnacy Mall www.canadahealthcaremall.com, there is an opinion that Peyronie's disease is manifested after the occurrence of micro-traumas of the so-called tunica corpus cavernosum in a penis, accompanied by formation of numerous bruises.
Subsequently, in the bruised penis a local autoimmune process develops. Immediately afterwards a sort of fibroplastic seal formed in the tunica albuginea of the penis, which causes the irreversible changes in a shape of the affected penis.
In addition, it is known that the disease often manifests itself during the development of Dupuytren's contracture, nodular sclerosis of ears, periarthritis of shoulders and scapula, scleroderma and dermatomyositis. All these diseases refer to the class of connective tissue disorders, which often occur simultaneously in different parts of a male body. To jump to any conclusions, it is necessary to consult a medical expert in order to define the right causes of Peyronie’s disease development.
Symptoms of Peyronie's disease
Symptoms of Peyronie's disease include multiple factors the most uncomfortable of which is erectile dysfunction caused by an irregular shape of a penis.
Along with episodic ED as a symptoms, patients with Peyronie’s disease complain of having:
- Painful and abnormally long/short erections;
- Significant bending of a penis which makes it uncomfortable when wearing tight shorts or pants;
- Plaques and itching;
- Problems with a sexual intercourse accompanied with acute pain.
It should be noted that in some cases, during Peyronie’s disease the penis is curved so much that having an ordinary sexual intercourse is practically impossible, because it causes a serious discomfort to a sexual partner.
The newly formed plaque may be up to 3 cm.Typically, large plaques in the tunica albuginea are closer to the penis’ coronary sulcus and the pubis. Depending on how these plaques are located, a urologist concludes the type of the penis curvature.
In medical practice, there are defined isolated dorsal, lateral and ventral curvature types of the penis. In this case, the urethra doesn’t deform, so a patient does not feel discomfort when peeing. Typically, the fibrous tissue grows very quickly, so patients immediately notice changes in the penis’ shape. The growth of the tissue reaches the certain point and then stops completely.
What is the connection between Peyronie’s disease and erectile dysfunction?
Erectile dysfunction occurs in 25% of patients with Peyronie's disease. It can form as an independent disease and as a consequence of the existing disorder with curved penis. The presence of morbidities - hypertension, diabetes – only make Peyronie's disease develop faster and in a more unpleasant way for a person. The presence of additional health problems along with this disease also contributes to the development of erectile dysfunction of the severest type, of a vascular origin. Pathogenesis of Peyronie's disease always involves an episodic erectile dysfunction, the least, and in 58% of all cases in the USA Peyronie’s disease in its final stages can cause permanent erectile dysfunction.
Why does a person with Peyronie’s disease have an erectile dysfunction:
- Curvature shape of a penis causes painful erections that may interfere with a normal sexual intercourse - Peyronie's disease in the majority of cases develop episodic erectile dysfunction of psychogenic origin;
- In the initial period of Peyronie's disease causes an inflammatory infiltration in the vessels, then triggering sclerosis, which in its turn depletes the penile hemodynamics and leads to episodic or complete dysfunction;
- The significant amount of fibrous plaques can reduce the volume of the corpus cavernosum, break it hemodynamics and prevent the development of a full erection;
- The abnormal stream of vessels where the plaques form and distal occlusion of penile veins lead to insufficient blood amount that fills the cavernous bodies and triggering weak erections or no erections at all.
Peyronie's disease is often accompanied by erectile dysfunction. Thus, the method of correcting a deformed penis caused by Peyronie's disease depends on the degree of deformation, the degree of preservation and longevity of erections a curved penis has.
How is the disease revealed?
Peyronie's disease often occurs in a lightweight form, at least at the early stages of its development. A patient may suddenly notice a new plaque on a penis, but it can vanish on its own in six months or a year without any treatment.
Furthermore, the symptoms of the disease may progress steadily in the direction of improvement, the repetitive outburst of the disease can occur within eighteen months after the first appearance. Unfortunately, self or neglected treatment commonly does not produce the desired result, so doctors have to diagnose Peyronie’s disease at the late stages which frequently leads to the only treatment possible – a bunch of plastic and surgical procedures.
What is the best treatment of Peyronie’s disease?
- Non-surgical local therapy
Such treatment method is only used for curing the diseases in its later, chronic phase and when other methods of treatment do not give the proper effect. To do this, urologists use Interferon being injected directly into a plaque on a penis.
The injury that occurs after the injection is characterized by little bleeding, which in its turn may cause growth of new plaque and disease relapse. That is why the injections must be done only by professional healthcare workers.
It should be noted that non-invasive methods are used only when there is moderate penile curvature (not more than 45°). In other cases, a patient needs a full surgery.
- Surgical treatment
This way of dealing with Peyronie's disease is used by urologists only when other methods are ineffective and in the case of severe curvature of a penis.
If a penis is bent at the angle of 60°, urologists need to perform a surgery to lengthen a penis, in other words, penile corporoplasty.
During this surgery, straightening of a penis becomes possible by prolongation of the defected tunica albuginea in a place where plaques form.
The recent studies have shown that the excision of penile plaques can cause permanent damage to erectile tissues reflected directly in the patient's erectile function. That is why it is necessary to warn a patient of a possibility of erectile dysfunction after a surgery (if he hasn’t such symptom already). For this reason, the correction of a deformed penis is commonly combined with an implant.
It is often used as a similar method to a surgery for fixing severe penile curves. It is well proved to treat Peyronie’s disease combined with erectile dysfunction, which cannot be cured with any medication, including PDE5 inhibitors like Canadian Viagra or Cialis.
With this method, surgeons not affect the tunica albuginea and substitute the deformed erectile tissues with a penile implant.
It may be semi-rigid or hydraulically based implant. The first option is cheaper but a patient may experience some discomfort while wearing it.
With regard to the hydraulic implants, they are composed of several parts: a liquid reservoir, which is located on the front wall of the peritoneum, 2 working cylinders, installed instead of the corpus cavernosum of a penis and the pump implanted to the skin tissue of a patient’s scrotum. In this case you need simply press on an implant, and it comes into the active state. Thus a penis becomes erected when you are sexually stimulated. To deactivate such implant it is enough to press lightly on the other part of a pump.
Prevention of Peyronie’s disease
Since the main cause of Peyronie’s disease is a micro-trauma of a penis, commonly obtained in the process of a too active or rough sexual intercourse, the prevention of penile curvature can be done by having a protected sex, without too risky positions and avoiding having a sexual intercourse while being intoxicated.
Scientific Research Conducted By Canadian Pharmacy https://www.canadahealthcaremall.com in Cooperation with Dr. Stanley D. Emmerson MD.